Celebrex (Celecoxib)

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Generic Name: Celecoxib
Brand Names: Celebrex
Dosage: 100mg, 200mg
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Celebrex (Celecoxib) has anti-inflammatory, analgesic and antipyretic action.

It is used to treat arthritis (rheumatoid arthritis, osteoarthritis), spondylitis, and acute pain.

Side effects

  • exacerbation of allergic diseases, flu syndrome, accidental injury, rarely – face edema;
  • peripheral edema, exacerbation of hypertension, increased blood pressure, arrhythmias, hot flashes, palpitations, tachycardia, rarely – congestive heart failure, ischemic stroke and myocardial infarction;
  • abdominal pain, diarrhea, dyspepsia, flatulence, tooth disease, rarely – vomiting;
  • dizziness, increased muscle tone, insomnia, anxiety, drowsiness, rarely – confusion;
  • urinary infection;
  • bronchitis, cough, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection;
  • itching, skin rash, rarely – alopecia, rash;
  • tinnitus, blurred vision;
  • loss of taste, loss of smell, aseptic meningitis, hallucinations;
  • hepatitis, liver failure, fulminant hepatitis, liver necrosis.

Precautions

Celebrex is contraindicated for patients with:

  1. hypersensitivity to any component of the drug or sulfonamides;
  2. bronchial asthma, urticaria or allergic reactions after ingestion of aspirin;
  3. peptic ulcer in the acute stage, or gastrointestinal bleeding;
  4. inflammatory bowel disease;
  5. heart failure;
  6. clinically confirmed coronary heart disease, peripheral artery disease and cerebrovascular disease in severe stages;
  7. severe hepatic and renal insufficiency;
  8. pregnancy and lactation.

How to take

The drug is taken orally.

The drug should be taken at the same time, regardless of the meal.

The maximum recommended daily dose for chronic administration is 400 mg.

Symptomatic treatment of osteoarthritis: the recommended dose is 200 mg per day for 1 or 2 doses.

Symptomatic treatment of rheumatoid arthritis: The recommended dose is 100 mg or 200 mg 2 times a day.

Symptomatic treatment of ankylosing spondylitis: The recommended dose is 200 mg per day for 1 or 2 doses.

Treatment of pain and primary dysmenorrhea: The recommended dose is 200 mg 2 times a day.

Drug interactions

As a result of the simultaneous use of warfarin, the risk of bleeding may increase.

Drug concentration in the blood can rise with concomitant administration with fluconazole, and ketoconazole.

ACE inhibitors and angiotensin may decrease an antihypertensive effect of Celebrex.

In combination with lithium, the blood level increases by approximately 17.

Missed dose

Take the capsule as soon as you remember. However, dont take the double dose and continue the prescribed dosage.

Overdose

Information regarding overdose is restricted. Specific signs of an overdose are unknown. However, more expressed symptoms of side effects should be expected.

It is necessary to carry out common activities aimed at the maintenance of respiratory function and cardiovascular system.

In case of severe overdose, contact emergency services immediately (USA/UK – 911 / 112 / 999).

Storage

The medicine should be kept in a dry place with temperature no higher than 30C, away from children.

Has a Generic Celebrex been approved?

Yes. The following products are equivalent to Celebrex:

celecoxib capsule;oral

  • Manufacturer: ALEMBIC PHARMS LTD
    Approval date: August 21, 2015
    Strength(s): 50MG, 100MG, 200MG, 400MG
  • Manufacturer: APOTEX INC
    Approval date: June 2, 2015
    Strength(s): 50MG, 100MG, 200MG
  • Manufacturer: AUROBINDO PHARMA LTD
    Approval date: February 1, 2016
    Strength(s): 50MG, 100MG, 200MG, 400MG
  • Manufacturer: CIPLA LTD
    Approval date: September 23, 2015
    Strength(s): 50MG, 100MG, 200MG, 400MG
  • Manufacturer: LUPIN LTD
    Approval date: October 29, 2014
    Strength(s): 50MG
  • Manufacturer: LUPIN LTD
    Approval date: June 9, 2015
    Strength(s): 100MG, 200MG, 400MG
  • Manufacturer: MYLAN PHARMS INC
    Approval date: May 30, 2014
    Strength(s): 50MG
  • Manufacturer: MYLAN PHARMS INC
    Approval date: February 11, 2015
    Strength(s): 100MG, 200MG, 400MG

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